CD46 antibody

Catalog No. ABIN119580

This anti-CD46 antibody is a Mouse Monoclonal antibody detecting CD46 in WB, FACS and IP. Suitable for Human.

Quick Overview for CD46 antibody (ABIN119580)

Target: CD46

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD46 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: MEM-258

Product Details anti-CD46 Antibody

Purification: Affinity chromatography on Protein A

Immunogen: HPB-ALL cell line

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: 1/10 - 1/50, use 10 μL of the suggested working dilution to label 10^6 cells. Immunoprecipitation. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CD46

Target: CD46

Alternative Name: CD46 / MCP

Background: CD46 functions as an inhibitor of complement activation limiting the formation and activity of C3 convertases. CD46 is expressed by all nucleated cells, often as multiple isoforms on the same cells. The molecule is also expressed by sperm and may be important in the process of fertilisation.Synonyms: MIC10, Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen

Gene ID: 9606

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization